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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCSH
All Species:
24.85
Human Site:
S434
Identified Species:
45.56
UniProt:
P14314
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14314
NP_001001329.1
528
59425
S434
L
C
P
F
K
L
V
S
Q
K
P
K
L
G
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542057
593
66107
S499
L
C
P
F
K
L
V
S
Q
K
P
K
L
G
G
Cat
Felis silvestris
Mouse
Mus musculus
O08795
521
58774
S427
L
C
P
F
K
L
V
S
Q
K
P
K
H
G
G
Rat
Rattus norvegicus
NP_001100276
525
59200
S431
L
C
P
F
K
L
V
S
Q
K
P
K
H
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510649
692
76488
S475
L
C
P
F
S
R
V
S
Q
K
P
K
H
G
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086185
514
57354
N419
V
Y
S
L
C
P
F
N
R
V
T
Q
K
P
K
Zebra Danio
Brachydanio rerio
NP_957347
529
59566
S435
L
C
P
F
N
R
V
S
Q
K
P
K
F
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609844
548
61521
A454
T
L
C
P
F
D
R
A
S
Q
K
S
R
S
G
Honey Bee
Apis mellifera
XP_625125
493
56012
V399
I
Y
T
L
C
M
F
V
K
A
T
Q
R
S
E
Nematode Worm
Caenorhab. elegans
NP_496073
507
58044
G414
T
Y
Q
F
C
P
F
G
Q
N
T
Q
K
D
T
Sea Urchin
Strong. purpuratus
XP_789169
523
60041
S428
L
C
P
F
E
K
S
S
Q
R
S
K
N
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146004
602
67827
C499
G
K
Y
T
Y
K
V
C
A
Y
K
K
A
S
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04924
702
79889
S609
D
E
K
S
D
L
I
S
N
L
A
A
I
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
80.9
N.A.
86.7
85.2
N.A.
53.6
N.A.
62.3
62.3
N.A.
38.3
41.4
36.7
43.7
Protein Similarity:
100
N.A.
N.A.
83.9
N.A.
92.9
91.6
N.A.
61.9
N.A.
77
76.7
N.A.
53.2
57.9
56.4
59.4
P-Site Identity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
80
N.A.
0
80
N.A.
6.6
0
13.3
60
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
80
N.A.
26.6
80
N.A.
20
26.6
20
73.3
Percent
Protein Identity:
N.A.
31.8
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
48.6
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
8
8
8
8
0
0
% A
% Cys:
0
54
8
0
24
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
8
0
0
0
0
0
0
0
8
8
% D
% Glu:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
62
8
0
24
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
0
8
0
0
0
0
0
54
62
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
8
8
0
31
16
0
0
8
47
16
62
16
0
8
% K
% Leu:
54
8
0
16
0
39
0
0
0
8
0
0
16
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
8
8
0
0
8
0
0
% N
% Pro:
0
0
54
8
0
16
0
0
0
0
47
0
0
8
0
% P
% Gln:
0
0
8
0
0
0
0
0
62
8
0
24
0
8
8
% Q
% Arg:
0
0
0
0
0
16
8
0
8
8
0
0
16
0
0
% R
% Ser:
0
0
8
8
8
0
8
62
8
0
8
8
0
24
0
% S
% Thr:
16
0
8
8
0
0
0
0
0
0
24
0
0
0
8
% T
% Val:
8
0
0
0
0
0
54
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
24
8
0
8
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _